Publication details

Depth of neuromuscular blockade and the perioperative conditions in laparoscopic surgery in pediatric population: Randomized controlled pilot trial

Authors

KLUČKA Jozef SZTURZOVÁ Kateřina KOSINOVÁ Martina KNOPPOVA Lenka ŤOUKÁLKOVÁ Michaela ŠTOUDEK Roman KRATOCHVÍL Milan TRCKOVA Alena KLINCOVÁ Martina KOVALČÍKOVÁ Petra PAVLÍK Tomáš PLÁNKA Ladislav TŮMA Jiří ŠTOURAČ Petr

Year of publication 2020
Type Article in Periodical
Magazine / Source JOURNAL OF CLINICAL ANESTHESIA
MU Faculty or unit

Faculty of Medicine

Citation
Web http://dx.doi.org/10.1016/j.jclinane.2019.109659
Doi http://dx.doi.org/10.1016/j.jclinane.2019.109659
Keywords Neuromuscular blockade; Surgical conditions; Laparoscopy; Surgery; Pediatric patient
Description Neuromuscular blockade (NMB) can facilitate intubation and lead to better intubation and surgical conditions. Preliminary data from the adult population favors the deep NMB for better surgical conditions [1–3], but they are still limited [4]. The primary aim of our trial was to compare surgical conditions during pediatric laparoscopic surgery in subgroups of patients with deep and moderate NMB. The secondary aim was to compare the incidence of complications between the groups. The primary hypothesis was that the deep NMB would lead to superior surgical conditions graded by the surgical scoring system and by the intraperitoneal pressure (lower pressure). This prospective randomized controlled single-blinded pilot study was conducted at a tertiary pediatric anesthesia center after Ethics committee approval (University Hospital in Brno, Czech Republic) and registered at clinicaltrials.gov (NCT02546843).
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