Publication details

Bi-Ligand Modification of Nanoparticles: An Effective Tool for Surface-Enhanced Raman Spectrometry in Salinated Environments

Authors

TYCOVA A. KLEPARNIK K. FORET František

Year of publication 2019
Type Article in Periodical
Magazine / Source NANOMATERIALS
MU Faculty or unit

Central European Institute of Technology

Citation
Web https://www.mdpi.com/2079-4991/9/9/1259/htm
Doi http://dx.doi.org/10.3390/nano9091259
Keywords ionic strength; nanoparticles; modification; myoglobin; saline solution; SERS; silver; sintering; stability; surface-enhanced Raman spectrometry
Description Elimination of massive aggregation of nanoparticles in the sample of high ionic strength is a prerequisite for the sensitive analysis through a surface-enhanced Raman spectrometry (SERS). We present a system of silver colloid modification composed of two thiolated modifiers (3-mercaptopropionic acid and thiolated polyethylene glycol) both creating a strong Ag-S bond. At their optimal molar ratio, the polymer acts as a steric barrier preventing direct nanoparticle-nanoparticle interaction, while the low-molecular organic acid creates areas accessible for the analyte molecules. Thus, this approach is an excellent tool for sustaining both the colloidal stability and SERS sensitivity. The functionality of the system was demonstrated on the SERS analysis of myoglobin from a saline solution. The favorable creation of hot spots was achieved by laser-induced sintering.
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