Publication details

Inovativní klinické designy a personalizovaná medicína v dětské onkologii

Title in English Innovative clinical designs and personalized medicine in pediatric oncology
Authors

ŠTĚRBA Jaroslav MARTINČEKOVÁ Alexandra KOZÁKOVÁ Šárka VALÍK Dalibor

Year of publication 2018
MU Faculty or unit

Faculty of Medicine

Citation
Description In the last decades of the last century, the fate of oncologically ill children has improved significantly and more than 80% of them have long-term remissions in developed countries. However, the first two decades of the new millennium have witnessed some stagnation in improving overall survival, and despite a better percentage of remissions achieved in a number of areas such as metastatic sarcomas, H3K27M mutated midline gliomas or some ependymomas, a significant percentage of patients are currently on treatment. inadequate, short-term or associated with very severe acute and long-term toxicity.

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