Publication details

Comparison of the effect of two anti-adhesion materials on the formation of postoperative adhesions after myomectomy – an experimental study on rabbit does

Authors

PÁNKOVÁ Soňa NEČASOVÁ Andrea LORENZOVÁ Jana JEKL Vladimír NEČAS Alois DUŠEK Ladislav HUDEČEK Robert GÁL Petr

Year of publication 2021
Type Article in Periodical
Magazine / Source Acta Veterinaria Brno
MU Faculty or unit

Faculty of Medicine

Citation
Web https://actavet.vfu.cz/90/4/0407/
Doi http://dx.doi.org/10.2754/avb202190040407
Keywords Lagomorpha; gynaecology; Hyalobarrier Gel; 4DryField® PH
Description This study compares the effect of Hyalobarrier Gel and 4DryField® PH on the formation of postoperative adhesions after myomectomy in an experimental study on rabbit does. Thirty experimental animals were divided into three groups: group A – control, group B – use of 4DryField® PH, and group C – use of the Hyalobarrier Gel. A simulated myomectomy was performed in each group. The animals were euthanised 14 days after the procedure and the antiadhesive effect of the above-mentioned preparations was evaluated according to the criteria. Statistical evaluation clearly showed differences in the antiadhesive effect in the scoring systems for groups B and C compared to control group A at a high level of significance. We demonstrated an obvious, statistically confirmed antiadhesive effect of the Hyalobarrier Gel and 4DryField® PH in an experimental model of the rabbit uterus. Comparing both preparations, the Hyalobarrier Gel shows a higher level of effectiveness. Based on the results of the experiment, both preparations can be unambiguously recommended for routine practice.

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