Publication details
NOVEL 1,3,5-TRIAZINYL AMINOBENZENESULFONAMIDES AS POTENT ANTI-VRE AGENTS
| Authors | |
|---|---|
| Year of publication | 2022 |
| Type | Appeared in Conference without Proceedings |
| MU Faculty or unit | |
| Citation | |
| Description | Carbonic anhydrases are metalloenzymes catalysing the reversible hydration of CO2, thereby affect the pH and affecting related physiological processes in various organisms. In pathogenic bacteria, CAs play an important role in survival and growth. Inhibition of bacterial CAs leads to growth retardation, growth defects and makes bacteria vulnerable to host defense mechanisms. Bacterial CAs are therefore a very promising target in the search for new antibiotics. |
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