Publication details

Leptospira interrogans sensu lato u volně žijících drobných savců z České republiky

Title in English Leptospira interrogans sensu lato in wild small mammals from the Czech Republic


Year of publication 2022
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Science

Description Introduction: Leptospirosis is a widespread zoonosis, affecting humans, domestic animals and wildlife, with small mammals as a reservoir of this infection. In recent years, this disease has been re-emerging and affecting approximately 1 million people all over the world each year. Due to this disease having a significant health impact, it is important to identify the source and method of infection. The risk of Leptospira sp. infection is higher mainly in cities of the developed and industrialised countries. The aim of the study was the detection of antibodies against Leptospira sp. in wild small mammals from the Czech Republic. Method: In total, samples of 855 animals trapped in three locations of Moravia during a six-year study (2010-2015) were examined by microscopic agglutination test, using 8 serovars of Leptospira interrogans sensu lato, representing serogroups Grippotyphosa, Icterohaemorrhagiae, Australis, Canicola, Sejroe, Javanica, Pomona and Pyrogenes, as antigens. Results: Antibodies to Leptospira sp. were detected in 6.1?% (52/855) of animals with a prevalence of 6.4?% (51/801) and 1.9?% (1/54) in rodents and insectivores, respectively. The only statistically significant difference (p ? 0.05) was in prevalence between individual species (0?% – 33?%), while there were no differences in sex (6.7?% in females and 5.1?% in males), localities (1.8?% – 8?%) and year of trapping (0?% – 8.4?%). Only two serovars L. interrogans serovar Pomona and L. interrogans serovar Grippotyphosa were detected in 5.5?% and 0.5?% of animals, respectively. Conclusion: The prevailing serovar of pathogenic L. interrogans s.l. can manifest itself in a number of infected people in the Czech Republic. The composition of vaccines should be based on the current occurrence of Leptospira serovars in the actual territory. For this reason, the occurrence of Leptospira and its serovars should therefore be regularly monitored.
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