Publication details

Bakterie rodu Anaplasma a Rickettsia

Title in English Bacteria of the genera Anaplasma and Rickettsia


Year of publication 2022
Type Conference abstract
MU Faculty or unit

Faculty of Science

Description Bacteria of the genera Anaplasma and Rickettsia are zoonotic pathogens that attack the blood system of humans and animals. Anaplasma sp. is typically replicated in the cytoplasmic vacuoles of granulocytes. Rickettsia sp. it attacks endothelial cells, to which it binds using the surface protein rOmpB and penetrates the cell by phagocytosis. Both genera include species that cause serious human disease. While the genus Anaplasma includes only one species, Anaplasma phagocytophilum, which is the causative agent of human granulocytic anaplasmosis, the genus Rickettsia includes several species pathogenic for humans. In general, these diseases are referred to as rickettsiosis and are divided into two groups: the typhoid group (TG) and the spotted fever group (SFG). It is evident that the number of cases of infection with these bacteria in the world is constantly increasing. The reason may be globalization and climate warming, as well as constant advances in detection methods. In the Czech Republic, this is a rare number of detected patients with these diseases. Although it has been confirmed that bacteria of the genus Anaplasma and Rickettsia occur in our territory, their detection does not belong to normal medical procedures and can thus often be mistaken for other similar infectious diseases. The presence of the genus Rickettsia spp was identified in the diploma theses of MU students. out of 1,367 ticks in 2011-2012, namely in the Brno Řečkovice locality in 3.6%, the Moravian Karst PLA 4.4% and the Bohemian-Moravian Highlands 4.1%. Anaplasma phagocytophilum was confirmed in 1,866 samples of Ixodes ricinus ticks collected in areas of southern Moravia in 2019 (Brno-Pisárky 2.8%); in Uherskobrodsk 1.8%; Brno Reservoir (Rakovec 1.45%). Furthermore, the presence of this bacterium was confirmed in ticks of the genera Dermacentor and Haemaphysalis. Specifically, it was in the Brno-Pisárky location in 2018 in one sample of A. phagogytophilum in a female H. concinna. The hypothesis of the presence of zoonotic pathogens in the genus Dermacentor and Haemaphysalis was also confirmed in 2020 in the area of South Moravia (Šídlovy skalky), where one positive male H. concinna was caught for A. phagocytophilum. This pathogen can also occur in these ticks in Poland. In cooperation with the University of Wroclaw, we managed to identify A. phagocytophilum also in a female D. reticulatus in the Polish locality near Wroclaw in the same year.
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