Publication details

Cervical Screening Clinical Practice Guideline: an adaptation of S3- Leitlinie Prävention des Zervixkarzinoms

Authors

VRBOVÁ Tereza DVOŘÁK Vladimír TURYNA Radovan DUŠKOVÁ Jaroslava TRNKOVÁ Markéta ONDRUŠ Jiří KLUGAR Miloslav

Year of publication 2022
Type Conference abstract
MU Faculty or unit

Faculty of Medicine

Citation
Description Background The determining cause of cervical carcinoma is Human Papilloma Virus infection. The aim of cervical screening is to reduce mortality and morbidity of cervical carcinoma by early diagnoses and treatment. Organized screening has proved reduced incidence of malignant tumours and mortality of cervical carcinoma. However, there is an ongoing discussion about lengths of screening intervals, age in patients and tests in order to identify high-grade lesions. Objective This project, a part of the Czech National Clinical Practice Guideline (CPG) Project, aimed to develop a trustworthy CPG, which would help diagnose cervical carcinoma in time, considering different tests, organizational structures, treatment management and screening participation. The CPG aims to decrease mid-term and long-term incidence and mortality in patients with cervical lesions and improve their quality of life. Methods & future prospects A systematic search yielded 43 (inter)nationl CPGs, which were compared against including and excluding criteria and assessed by AGREEII tool. The working group has adapted German guideline “Prävention des Zervixkarzinoms”. Most of the recommendations were adopted and contextualized, only legal distinctions were considered. There are international differences regarding the lowest and highest ages for organised cervical screening, there is a lack of studies in patients over 65. In the Czech Republic, women are granted prevention gynaecological examination (and opportunity screening) from the age of 15, women between 25 and 65 are included in organised screening. The working group of the CPG suggest a nationwide 3-arm-study regarding screening intervals for a transitive period, before any change in legislation is suggested.

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