Publication details

Acute kidney injury requiring renal replacement therapy due to Clostridioides difficile infection in a 15-year-old boy

Authors

PAPEŽ Jan ŠTARHA Jiří DOLEŽEL Zdeněk HOMOLA Lukáš JABANDŽIEV Petr

Year of publication 2022
Type Article in Periodical
Magazine / Source EPIDEMIOLOGIE MIKROBIOLOGIE IMUNOLOGIE
MU Faculty or unit

Faculty of Medicine

Citation
Web https://www.prolekare.cz/casopisy/epidemiologie/2022-4-23/akutni-poskozeni-ledvin-s-nutnosti-eliminacni-lecby-jako-dusledek-infekce-clostridioides-difficile-u-15leteho-chlapce-133355
Keywords diarrhea; Clostridioides difficile; acute kidney injury; hemodialysis; child
Description Acute gastroenteritis is commonly seen in pediatric clinical practice. It is a largely self-limited disease with a benign course. We present a case of teenager with gastroenteritis resulting in severe acute kidney injury. The decline in glomerular filtration was so significant that renal replacement therapy had to be initiated. We had to continue in intermitent hemodialysis for seven days until sufficient improvement in renal function. Clostridioides difficile was identified as a cause of vomiting, bloody diarrhea and subsequent dehydration. To our knowledge, this is the first reported case of C. difficile-associated diarrhea accompanied by acute kidney injury requiring renal replacement therapy in a child.

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