Publication details
Novel fluorophores applicable for glycan detection
| Authors | |
|---|---|
| Year of publication | 2023 |
| Type | Conference abstract |
| MU Faculty or unit | |
| Citation | |
| Description | Changes in the composition of glycans correlate with the progression of many diseases; therefore, they are investigated as disease markers. Unfortunately, their analysis is complicated because they do not contain a chromophore or charges that would enable their electrophoretic separation. Our idea was to develop a new fluorescent marker covalently bound to glycans providing fast labeling kinetics, high quantum yield, increased detection sensitivity using MS, and at the same time, carrying a charge in the structure, which will enable the studied glycans to be separated electrophoretically |
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