Publication details

New insight into the biocompatibility/toxicity of graphene oxides and their reduced forms on Chlamydomonas reinhardtii

Authors

BYTESNIKOVA Zuzana KOLACKOVA Martina DOBESOVA Marketa SVEC Pavel RIDOSKOVA Andrea PEKARKOVA Jana PŘIBYL Jan CAPAL Petr HUSKA Dalibor ADAM Vojtech RICHTERA Lukas

Year of publication 2023
Type Article in Periodical
Magazine / Source NANOIMPACT
MU Faculty or unit

Central European Institute of Technology

Citation
Web https://www.sciencedirect.com/science/article/pii/S2452074823000198?via%3Dihub
Doi http://dx.doi.org/10.1016/j.impact.2023.100468
Keywords Graphene oxide; Reduction; Toxicity; Biocompatibility; Chlamydomonas; Microalgae
Description Graphene oxides (GOs) and their reduced forms are often discussed both positively and negatively due to the of information about their chemistry and structure. This study utilized GOs with two sheet sizes that were further reduced by two reducing agents (sodium borohydride and hydrazine) to obtain two different degrees reduction. The synthesized nanomaterials were characterized using scanning electron microscopy (SEM), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), elemental analysis (EA), Fourier transform infrared (FTIR) spectroscopy, and Raman spectroscopy (RA) to understand their chemistry and structure. second focus of our investigation included in vitro testing of the biocompatibility/toxicity of these materials model organism, the freshwater microalga Chlamydomonas reinhardtii. The effects were studied on the basis biological endpoints complemented by biomass investigation (FTIR spectroscopy, EA, and atomic absorption spectrometry (AAS)). The results showed that the biocompatibility/toxicity of GOs is dependent on chemistry and structure and that it is impossible to generalize the toxicity of graphene-based nanomaterials.
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