Publication details

Development of hard enteric capsules by the immersion coating method

Authors

FRANC Aleš FÜLÖPOVÁ Nicole PAVLOKOVÁ Sylvie DEBONO Ivan VETCHÝ David

Year of publication 2024
Type Appeared in Conference without Proceedings
MU Faculty or unit

Faculty of Pharmacy

Citation
Description Research focuses on drug absorption outside the stomach due to the instability of many drugs in its acidic environment. A simple lab process coats DRcapsTM hard capsules with enteric polymers. These capsules, filled with caffeine, are immersed in Eudragit® S 100, Acryl-EZE®, and Cellacefate dispersions at three different concentrations, then dried. The goal is to identify the optimal polymer type and concentration for delayed release, evaluated via a two-step pH change disintegration and dissolution test.

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