Publication details
Baroreflex sensitivity determined by spectral method and heart rate variability, and two-years mortality in patients after myocardial infarction.
| Authors | |
|---|---|
| Year of publication | 2000 |
| Type | Article in Periodical |
| Magazine / Source | Physiological Research |
| MU Faculty or unit | |
| Citation | |
| Field | Physiology |
| Keywords | Baroreflex sensitivity; spectral analysis; myocardial infarction; cardiac death; risk stratification. |
| Description | The impact of an autonomic dysfunction (AD) on mortality in patients after myocardial infarction was evaluated. We examined 162 patients (20 died in two years after myocardial infarction). Baroreflex sensitivity BRS<3ms/mmHg (spectral analysis of spontaneous fluctuations of systolic blood pressure and cardiac intervals) and/or SDNN index<30ms (from 24-hour ECG recording) were taken as markers of AD. The risk stratification was performed according to the number of following standard risk factors (SRF): ejection fraction;40%, positive late potentials and presence of ventricular extrasystoles;10/hour. In 92 patients without SRF, there was no difference in mortality between patients with AD (4%) and without AD (4.5%). In 6 patients with three SRF, mortality was 66.6%. Of 64 patients with one or two SRF, 32 had AD. Mortality was 6.25% in patients without AD and 31.2% in those with AD (p<0.025). AD increased five times the two years mortality in patients with moderate risks. |
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