Publication details

Dynamics of clinical response to paroxetine in coherence with CYP 2D6 metabolic status during long-term therapy of depressive disorder.

Authors

HADAŠOVÁ Eva ŽOURKOVÁ Alexandra ZELENKOVÁ Olga

Year of publication 2001
Type Article in Periodical
Magazine / Source South African Journal of Science
MU Faculty or unit

Faculty of Medicine

Citation
Field Psychiatry, sexuology
Keywords Genetic polymorphism; cytochrome P450; SSRI; psychiatry; sexual disorder
Description Long-term therapy with SSRI antidepressants can evoke adverse effects including sexual disorders which may be more pronounced in patients with decreased activity of CYP 2D6, either given by the defect of the enzyme expression or evoked by previous treatment with enzyme inhibitors.
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