Publication details
Computer modelling of effect of transversal tubules on excitation - contraction coupling in cardiac cells (Basic study)
| Authors | |
|---|---|
| Year of publication | 2001 |
| Type | Article in Proceedings |
| Conference | Engineering Mechanics 2001 |
| MU Faculty or unit | |
| Citation | |
| Field | Biophysics |
| Keywords | cardiac cell; T-system; quantitative modelling |
| Description | The transverse tubular system (T-system) of cardiac muscle is a structure that allows rapid propagation of excitation into the cell interior. As suggested in many resent experimental works it could have a significant effect on cardiac cell function induced by the accumulation or the depletion of ions in restricted tubular space. The aim of our work was to design a mathematical model of electrical activity of cardiac cell including a quantitative description of T-system function and to explore the physio-logical significance of T-system in excitation-contraction coupling quantitatively. |
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