Publication details

Zhodnocení dosavadních zkušeností s dynamikou aktivity CYP2D6

Title in English Evaluation of the current experience with the dynamics of CYP2D6 activity
Authors

ZELENKOVÁ Olga ČEŠKOVÁ Eva HADAŠOVÁ Eva ŽOURKOVÁ Alexandra

Year of publication 2002
Type Article in Periodical
Magazine / Source Psychiatrie
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords Genetic polymorphism; CYP2D6; psychiatry; enzyme inhibition;
Description The study followed the dynamics of the metabolic capacity of CYP2D6 during the 28-day treatment with various psychotropic drugs. It was confirmed that the psychopharmacotherapy may change the CYP2D6 phenotype from the extensive (EM) to the poor (PM) metabolic phenotype.
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