Publication details
T Lymphocyte Therapy of Cancer
| Authors | |
|---|---|
| Year of publication | 2004 |
| Type | Article in Periodical |
| Magazine / Source | Physiological Research |
| MU Faculty or unit | |
| Citation | |
| Web | http://biomed.cas.cz |
| Field | Immunology |
| Keywords | T lymphocyte; Cancer; Therapy |
| Description | The rationale for the use of T lymphocytes to fight cancer is the immunogenicity of tumor cells.T cells are capable to recognize and finally to kill tumor cells.Adoptiveč cell transfer therapies provide the opportunity to overcome tolerogenic mechanisms by enabling the selection and activation of highly reactive T cell subpopulations and bymanipulation of the host environment into which the T cell are introduced. The aim of this article is to review the possibilities,limitations and recent clinical experience with this novel anticancer treatment,namely with adoptive immunotherapy using antigen-specific T cells. |
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