Publication details

Stanovení diklofenaku a 4-hydroxydiklofenaku jako markeru metabolické aktivity CYP2C9

Title in English Determination of diclofenac and 4-hydroxydiclofenac as a probe substrate of CYP2C9
Authors

JUŘICA Jan TOMANDL Josef ZAHRADNÍKOVÁ Lucia DOSTÁLEK Miroslav HADAŠOVÁ Eva

Year of publication 2005
Type Article in Proceedings
Conference Sborník abstrakt 34. konference Syntéza a analýza léčiv- Nové směry ve výzkumu léčiv
MU Faculty or unit

Faculty of Medicine

Citation
Field Pharmacology and pharmaceutical chemistry
Keywords Diclofenac; CYP2C9; determination
Description Diclofenac 4-hydroxylation is commonly used for the CYP2C9 metabolic evaluation. A new rapid, simple and sensitive HPLC method for determination of diclofenac and 4-hydroxydiclofenac was developed.
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