Publication details

Basic fibroblast growth factor and its receptors in human embryonic stem cells

Authors

DVOŘÁK Petr HAMPL Aleš

Year of publication 2005
Type Article in Periodical
Magazine / Source Folia histochemica et cytobiologica
MU Faculty or unit

Faculty of Medicine

Citation
Field Genetics and molecular biology
Keywords stem cells
Description Human embryonic stem cells (hESCs) are pluripotent stem cells with long-lasting capacity to self-renew and differentiate into various cell types of endodermal, ectodermal or mesodermal origin. The purpose of this review is to summarize recent data on the expression of FGFs and their receptors in hESCs, and critically evaluate the potential effects of FGF signals for their undifferentiated growth and/or differentiation in context with our current understanding of FGF/FGFR biology.

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