Publication details
trans-Bis{2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine-N7}platinum(II) dimethylformamide disolvate
| Authors | |
|---|---|
| Year of publication | 2006 |
| Type | Article in Periodical |
| Magazine / Source | Acta Crystallographica Section E: Structure Reports Online |
| MU Faculty or unit | |
| Citation | |
| Field | Inorganic chemistry |
| Keywords | cyclin-dependent kinase; CDK inhibitor; anti-cancer; transition metal complex; platinum complex |
| Description | The title complex, trans-[PtIICl2(C15H16ClN5O)2].2C3H7NO, is centrosymmetric, with square-planar coordination of the Pt atom within a trans-Cl2N2 donor set. The complex is connected through O-H...O hydrogen bonds to two dimethylformamide solvent molecules. The complex is the first structural example of a Pt(II) complex involving two coordinated cyclin-dependent kinase inhibitors, viz. 2-chloro-6-[(3-hydroxybenzyl)amino]-9-isopropylpurine. |
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