Publication details
Polymorphisms of glutathione S-transferase (GST) M1, T1, and P1 in patients with reflux esophagitis and Barretts esophagus
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | J Hum Genet |
| MU Faculty or unit | |
| Citation | |
| Field | Surgery incl. transplantology |
| Keywords | GERD; GSTs; glutathione S-transferase; polymorphism; reflux esophagitis; gene; Barretts esophagus |
| Description | Reflux esophagitis (RE) and Barretts esophagus belong to the most common esophageal complications of gastroesophageal reflux disease. Glutathione S-transferase (GST) enzymes play an important role in cellular protection against oxidative stress and toxic foreign chemicals. Therefore, we investigated the hypothesis that polymorphisms in genes for these detoxifying enzymes could influence susceptibility to RE and Barretts esophagus. |
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