Publication details

Evaluation of benzophenanthridine alkaloids content in the selected species of family Papaveraceae

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JANA Suchomelová TÁBORSKÁ Eva

Year of publication 2006
Type Article in Proceedings
Conference Chemistry, Pharmacology and Biosynthesis of Alkaloids
MU Faculty or unit

Faculty of Medicine

Field Plant cultivation
Keywords Benzophenanthridine alkaloids; Papaveraceae; HPLC
Description Using HPLC method we analyzed the content (as the weight % of dry root) of alkaloids in the root extracts of selected species of family Papaveraceae. Reversed column MAX RP C 12 Phenomenex Synergi was used, mobile phase consisted of heptansulfonic acid with triethanolamine in redistilled water, pH 2,5.Acetonitrile gradient 25 60% during 30 minutes.The highest content of sanguinarine and chelerythrine was found in root of Dicranostigma lactucoides. The rare minor alkaloids chelirubine, chelilutine and macarpine were detected in Macleaya microcarpa and Stylophorum lasiocarpum. The presence of sanguirubine was approved only in Sanguinaria canadensis.
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