Impact of inaccurate knowledge of experimental stimulus time-course on GLM fMRI analysis

• Authors: MIKL Michal; DRASTICH Aleš; HLUŠTÍK Petr; MAREČEK Radek; BRÁZDIL Milan
• Year of publication: 2007
• Type: Conference abstract
• MU Faculty or unit: Faculty of Medicine
• Description: In functional magnetic resonance imaging (fMRI), detection of activation is often realized using the general linear model (GLM). The measured signal is modeled using convolution of stimulus time-course and hemodynamic response function (HRF). Both accurate knowledge of experimental stimulus time-course and accurate knowledge of HRF are necessary to obtain valid and meaningful results. The aim of this work is to find how much the results depend on inaccurate knowledge of stimulus time-course

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