Publication details
Effective connectivity in target stimulus processing: A dynamic causal modeling study of visual oddball task.
| Authors | |
|---|---|
| Year of publication | 2007 |
| Type | Article in Periodical |
| Magazine / Source | Neuroimage |
| MU Faculty or unit | |
| Citation | |
| Field | Neurology, neurosurgery, neurosciences |
| Keywords | fMRI; Target detection; Oddball paradigm; Connectivity; Dynamic causal modeling |
| Description | To investigate the fundamental connectivity architecture of neural structures involved in the goal-directed processing of target events, twenty healthy volunteers underwent event-related functional magnetic resonance imaging (fMRI) while performing a standard oddball task. Dynamic causal modeling (DCM) was used to compare competing neurophysiological models with different intrinsic connectivity structures and input regions within the network of brain regions underlying target stimulus processing. Our findings indicate that during target stimulus processing there is a bidirectional frontoparietal information flow, very likely reflecting parallel activation of two distinct but partially overlapping attentional or attentional/event-encoding neural systems. Additionally, a simple hierarchy within the right frontal lobe is suggested with the ACC exerting influence over the PFC. |
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