Publication details

Macugen v léčbě vlhké formy věkem podmíněné makulární degenerace

Title in English Macugen in treatment of wet form of age related macular degeneration
Authors

KOLÁŘ Petr

Year of publication 2008
Type Article in Periodical
Magazine / Source Oftalmochirurgie
MU Faculty or unit

Faculty of Medicine

Citation
Field ORL, ophthalmology, stomatology
Keywords age related macular degeneration; choroidal neovascular membrane; vascular endothelial growth factor; pegaptanib
Description Discovery of endothelial growth factor antagonists radical affected therapy of the wet form of age related macular degeneration. The first approved antagonist is pegaptanib (Macugen) that selectively blocked VEGF-165 isoform. This isoform is responsible for initialising of pathological neovascularization.

You are running an old browser version. We recommend updating your browser to its latest version.

More info