Publication details

Chromatin structure and epigenetics of tumour cells: a review.

Authors

BÁRTOVÁ Eva KREJČÍ J. HÁJEK Roman HARNIČAROVÁ Andrea KOZUBEK Stanislav

Year of publication 2009
Type Article in Periodical
Magazine / Source Cardiovascular & Hematological Disorders - Drug Targets
MU Faculty or unit

Faculty of Science

Citation
Field Genetics and molecular biology
Keywords chromatin; epigenetics;
Description Tumour cells are characterized by karyotype instability, which is accompanied by specific events in the chromatin structure and epigenetic patterns. Epigenetics involves heritable changes in the physical and biochemical state of chromatin, which have no effect on DNA sequences; therefore, changes in the nuclear radial arrangement of chromosomes can also be considered epigenetic events.
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