Chromatin structure and epigenetics of tumour cells: a review.
|Year of publication||2009|
|Type||Article in Periodical|
|Magazine / Source||Cardiovascular & Hematological Disorders - Drug Targets|
|MU Faculty or unit|
|Field||Genetics and molecular biology|
|Description||Tumour cells are characterized by karyotype instability, which is accompanied by specific events in the chromatin structure and epigenetic patterns. Epigenetics involves heritable changes in the physical and biochemical state of chromatin, which have no effect on DNA sequences; therefore, changes in the nuclear radial arrangement of chromosomes can also be considered epigenetic events.|