Publication details

Increasing the infliximab dose in rheumatoid arthritis patients: a randomized, double blind study failed to confirm its efficacy.

Authors

PAVELKA Karel JAROŠOVÁ Kateřina SUCHÝ David ŠENOLD Ladislav CHROUST Karel DUŠEK Ladislav VENCOVSKÝ Jiří

Year of publication 2009
Type Article in Periodical
Magazine / Source Annals of the Rheumatic Diseases
MU Faculty or unit

Faculty of Medicine

Citation
Field Other medical specializations
Keywords rheumatoid arthritis; therapy; infliximab; dose escalation
Description In this study, increasing the infliximab dose from 3 to 5 mg/kg in RA patients with residual disease activity did not improve efficacy but moderately increased toxicity. These data indicate that a switch to another biological treatment would be a more appropriate strategy in incomplete responders.

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