HOTSPOT WIZARD 1.0

• Authors: PAVELKA Antonín; CHOVANCOVÁ Eva; DAMBORSKÝ Jiří
• Year of publication: 2008
• MU Faculty or unit: Faculty of Science
• Web: Počítačový program pro racionální design mutací
• Description: HotSpot Wizard is a tool for automatic identification of hot spot sites for engineering of substrate specificity, activity or enantioselectivity of enzymes. HotSpot Wizard integrates several bioinformatics databases and computational tools and represents an easy way to perform several structural and evolutionary analyses at once with minimal demands on users, making this server potentially useful for experimentalists with no prior knowledge of computer modelling or rational protein design.

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