Publication details

Influence of Phosphorus Acid Pendant Arms on Solution Properties of Metal Complexes of Polyazamacrocycles

Authors

HERMANN Petr LUBAL Přemysl KOTEK Jan

Year of publication 2009
Type Article in Proceedings
Conference Abstract Book of ISABC 10 conference (International Symposium on Applied Bioinorganic Chemistry)
MU Faculty or unit

Faculty of Science

Citation
Field Inorganic chemistry
Keywords macrocyclic ligands; metal complexes; MRI; nuclear and optical methods
Description Complexes of macrocyclic ligands are widely used in medicine (MRI, nuclear and optical methods) for diagnosis and/or therapy. Molecular imaging utilizing the metal complexes is an emerging field of medical/biological research. The complexes considered must be highly stable under competing conditions. Acid-assisted decomplexation kinetics is a method of choice for assesment of kinetic inertness of the complexes. Relations between structures of ligands and thermodynamic and kinetic stability of their complexes will be discussed.

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