Publication details

Revisiting the planarity of nucleic acid bases: Pyramidilization at glycosidic nitrogen in purine bases is modulated by orientation of glycosidic torsion

Authors

SYCHROVSKÝ Vladimír FOLDÝNOVÁ-TRANTÍRKOVÁ Silvie ŠPAČKOVÁ Naděžda ROBEYNS Koen VAN MEERVELT Luc BLANKENFELDT Wulf VOKÁČOVÁ Zuzana ŠPONER Jiří TRANTÍREK Lukáš

Year of publication 2009
Type Article in Periodical
Magazine / Source Nucleic Acids Research
MU Faculty or unit

Faculty of Science

Citation
Field Biophysics
Keywords bases of nucleic acids; molecular dynamics; NMR; quantum chemistry
Description We describe a novel, fundamental property of pyramidilization at the N1/9 sites of purine and pyrimidine bases. The study combines analyses of ultra-highresolution X-ray structures together with quantum chemical calculations, molecular dynamics simulations, and published solution nuclear magnetic resonance data.
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