Impact of repeated methamphetamine pretreatment on intravenous self-administration of the drug in males and estrogenized or non- estrogenized ovariectomized female rats.

• Authors: KUČEROVÁ Jana; VRŠKOVÁ Dagmar; ŠULCOVÁ Alexandra
• Year of publication: 2009
• Type: Article in Periodical
• Magazine / Source: Neuroendocrinology Letters
• MU Faculty or unit: Faculty of Medicine
• Web: http://www.ncbi.nlm.nih.gov/pubmed/20035259?itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum&ordinalpos=1
• Field: Pharmacology and pharmaceutical chemistry
• Keywords: methamphetamine; self-administration; behavioral sensitization; gender differences; rats
• Description: The model of i.v. self-administration of methamphetamine combined with fourteen days of intermittent pretreatment with MET was used to evaluate the influence of behavioral sensitization to the drug on the spontaneous intake in i.v. self-administration sessions in male and female ovariectomized rats with and without natural estrogen substitution.

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