Publication details

Genetic conflict outweighs heterogametic incompatibility in the mouse hybrid zone?

Authors

MACHOLÁN Miloš BAIRD Stuart J. E. MUNCLINGER Pavel DUFKOVÁ Petra BÍMOVÁ Barbora PIÁLEK Jaroslav

Type Article in Periodical
Magazine / Source BMC Evolutionary Biology
MU Faculty or unit

Faculty of Science

Citation
Web http://www.biomedcentral.com/1471-2148/8/271
Field Zoology
Keywords house mouse; hybrid zone; genetic conflict; Y chromosome
Description The Mus musculus musculus/M. m. domesticus contact zone in Europe is characterised by sharp frequency discontinuities for sex chromosome markers at the centre of wider clines in allozyme frequencies.We identify a triangular area (approximately 330 km2) where the musculus Y chromosome introgresses across this front for up to 22 km into domesticus territory. Introgression of the Y chromosome is accompanied by a perturbation of the census sex ratio: the sex ratio is significantly female biased in musculus localities and domesticus localities lacking Y chromosome introgression. In contrast, where the musculus Y is detected in domesticus localities, the sex ratio is close to parity, and significantly different from both classes of female biased localities. The geographic position of an abrupt cline in an X chromosome marker, and autosomal clines centred on the same position, seem unaffected by the musculus Y introgression.We conclude that sex ratio distortion is playing a role in the geographic separation of speciation genes in this section of the mouse hybrid zone. We suggest that clines for genes involved in sex-ratio distortion have escaped from the centre of the mouse hybrid zone, causing a decay in the barrier to gene flow between the two house mouse taxa.