Publication details

High-performance analysis of biological systems dynamics with the DiVinE model checker

Investor logo
Investor logo


Year of publication 2010
Type Article in Periodical
Magazine / Source Briefings in Bioinformatics
MU Faculty or unit

Faculty of Informatics

Field Informatics
Keywords molecular interaction networks; mathematical modeling and computer simulation; kinetic models; discrete abstraction; high-performance computing; model checking
Description The current interest in systems biology is to gain a better understanding of how the complex dynamic behaviour of the cell emerges from mutual interactions of molecular species. When solving such a nontrivial goal, biological data have to be necessarily integrated with mathematical modelling and computer analysis. Since the key aspect of biological modelling is based on unifying several kinds of data captured in terms of large-scale biological networks, scalable and automatized methods are necessary to obtain novel predictions and understanding. In this review, we provide a brief description of the tool DiVinE adapted for automatized analysis of biological systems dynamics. The tool employs high-performance computing techniques to enable analysis of large models.
Related projects:

You are running an old browser version. We recommend updating your browser to its latest version.

More info