Aspergillus fumigatus lectins - how to stay in touch

• Title in English: Aspergillus fumigatus lectins - how to stay in touch
• Authors: HOUSER Josef; KOMÁREK Jan; KOSTLÁNOVÁ Nikola; CIOCCI Gianluca; IMBERTY Anne; WIMMEROVÁ Michaela
• Year of publication: 2010
• Type: Conference abstract
• MU Faculty or unit: Faculty of Science
• Description: Saprophytic fungus Aspergillus fumigatus is widespread alergen and an important pathogen for immunocompromised patients as well. Typical way, which many pathogens including Aspergillus utilize for binding to host-cells, is via sugar-binding proteins - lectins. In our research group we combine structural and functional approaches to precisely describe lectins' binding properties. Together with bioinformatics and molecular modeling we build up a complex picture of these biologicaly and medicaly important macromolecules.

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