Publication details

Aspergillus fumigatus lectins - how to stay in touch

Title in English Aspergillus fumigatus lectins - how to stay in touch
Authors

HOUSER Josef KOMÁREK Jan KOSTLÁNOVÁ Nikola CIOCCI Gianluca IMBERTY Anne WIMMEROVÁ Michaela

Year of publication 2010
Type Conference abstract
MU Faculty or unit

Faculty of Science

Citation
Description Saprophytic fungus Aspergillus fumigatus is widespread alergen and an important pathogen for immunocompromised patients as well. Typical way, which many pathogens including Aspergillus utilize for binding to host-cells, is via sugar-binding proteins - lectins. In our research group we combine structural and functional approaches to precisely describe lectins' binding properties. Together with bioinformatics and molecular modeling we build up a complex picture of these biologicaly and medicaly important macromolecules.
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