High-affinity lectins from pathogens: the potential targets for antiadhesive drug design

• Authors: ŠULÁK Ondřej; MALINOVSKÁ Lenka; CIOCI Gianluca; HOUSER Josef; KOSTLÁNOVÁ Nikola; LAMEIGNERE Emilie; POKORNÁ Martina; IMBERTY Anne; WIMMEROVÁ Michaela
• Year of publication: 2010
• Type: Article in Periodical
• Magazine / Source: Materials Structure in Chemistry, Biology, Physics and Technology
• MU Faculty or unit: Faculty of Science
• Field: Biochemistry
• Keywords: lectin; antiadhesive therapy
• Description: Protein-carbohydrate interactions play an important role in many biologically relevant processes. The contribution is focused on lectins from human opportunistic pathogens, which display sub-micromolar range affinity towards their carbohydrate ligands.

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