Publication details

Method of detoxication of yperite by using haloalkane dehalogenases

Authors

PROKOP Zbyněk DAMBORSKÝ Jiří OPLUŠTIL František FOŘTOVÁ Andrea NAGATA Yuji

Year of publication 2010
Type Patent
MU Faculty or unit

Faculty of Science

Publisher Patentový úřad Nový Zéland
State New Zealand
Patent's number NZ 564218
Description Patent granted in New Zeland "Method of detoxication of yperite by using haloalkane dehalogenase".The method of detoxification of yperite by the use of haloalkane dehalogenases or their compositions, the method of preparation of dehalogenationating enzymes and of decontamination compositions which contain at least one wild type and/or modified haloalkane dehalogenase (EC 3.8.1.5) as an chemically active component. The preferred dehalogenases are DhaA from Rhodococcus rhodochrous NCIMB 13064, DmbA from Mycobacterium bovis 5033/66 or LinB from Sphingomonas paucimobilis UT26. Decontamination is utilized for detoxification of yperite from the surfaces of instrumentality, constructional objects, the people’s or animal’s skin and elements of environment, when yperite is exposed to the action of decontamination composition at +10 C to +70 C, preferably at +40C and pH = 4 to 12.

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