Publication details

Mikroprostředí kostní dřeně a jeho role v patogenezi leukemií

Title in English Bone marrow microenvironment and its role in the pathogenesis of leukaemia
Authors

LÉTALOVÁ Eva DOUBEK Michael FOLBER František VERNER Jan MRÁZ Marek POSPÍŠILOVÁ Šárka MAYER Jiří

Year of publication 2011
Type Article in Periodical
Magazine / Source Transfuze a hematologie dnes
MU Faculty or unit

Central European Institute of Technology

Citation
Field Oncology and hematology
Keywords haematopoiesis; bone marrow microenvironment; haematopoieticstem cell niche
Description Bone marrow microenvironment plays a key role in the process of haematopoiesis. It has a supportive function for quiescent haematopoietic stem cells located in so called niches. It provides appropriate conditions for haematopoietic stem cell differentiation and for the proliferation of blood elements.

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