Publication details

Tranzitorní hyperfosfatazemie

Title in English Transient hyperphosphatasemia
Authors

DOLEŽEL Zdeněk PAPEŽ Jan RÁČILOVÁ Zdeňka PINKASOVÁ Tereza

Year of publication 2012
Type Article in Periodical
Magazine / Source Pediatrie pro praxi
MU Faculty or unit

Faculty of Medicine

Citation
Field Paediatry
Keywords alkaline phosphatase; transient hyperphosphatasemia; childhood
Description Transient hyperphosphatasemia (TH) of infancy and childhood is a temporary and isolated increase of serum alkaline phosphatase (ALP-s) activity occurring without obvious cause usually during the first five years of life. The diagnosis of TH is established after finding of a transient but marked ALP-s elevation in the absence of clinical or laboratory findings of bone or liver disease. ALP-s returns to normal in a few months. TH has not been found to be life-threatening and is classified as a benign phenomenon. We report a clinical case of a toddler with TH and a literature review. This condition should be recognized by pediatricians in order not to put patiens throught lengthy, expensive and unnecessary investigation.

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