Mgr. Stjepan Uldrijan, CSc.
Head of the research group, Stjepan Uldrijan Research Group
Office: bldg. B06/317
Kamenice 753/5
625 00 Brno
Phone: | +420 549 49 4040 |
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E‑mail: |
social and academic networks: |
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Total number of publications: 79
2019
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A Single Conserved Amino Acid Residue as a Critical Context-Specific Determinant of the Differential Ability of Mdm2 and MdmX RING Domains to Dimerize
Frontiers in Physiology, year: 2019, volume: 10, edition: APR 9 2019, DOI
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BENZIMIDAZOLES DOWNREGULATE MDM2 AND MDMX AND ACTIVATE P53 IN MDMX OVEREXPRESSING TUMOR CELL
Year: 2019, type: Conference abstract
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Benzimidazoles Downregulate Mdm2 and MdmX and Activate p53 in MdmX Overexpressing Tumor Cells
Molecules, year: 2019, volume: 24, edition: 11, DOI
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Furo[3,2-b]pyridine: A Privileged Scaffold for Highly Selective Kinase Inhibitors and Effective Modulators of the Hedgehog Pathway
Angewandte Chemie International Edition, year: 2019, volume: 58, edition: 4, DOI
2018
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Induction of cancer cell stemness by depletion of macrohistone H2A1 in hepatocellular carcinoma
Hepatology, year: 2018, volume: 67, edition: 2, DOI
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Metabolic stress regulates ERK activity by controlling KSR-RAF heterodimerization
EMBO reports, year: 2018, volume: 19, edition: 2, DOI
2017
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A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein
Plos one, year: 2017, volume: 12, edition: 10, DOI
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Inhibitor repurposing reveals ALK, LTK, FGFR, RET and TRK kinases as the targets of AZD1480
Oncotarget, year: 2017, volume: 8, edition: 65, DOI
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Ubiquitin-specific peptidase 48 regulates Mdm2 protein levels independent of its deubiquitinase activity
Scientific Reports, year: 2017, volume: 7, edition: FEB 24 2017, DOI
2016
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Substituted 2-hydroxy-N-(arylalkyl)benzamide sensitizes cancer cells to metabolic stress by disrupting actin cytoskeleton and inhibiting autophagic flux
Toxicology in Vitro, year: 2016, volume: 37, edition: "neuvedeno", DOI