Liam Keegan, PhD.

2021

• The effects of RNA editing in cancer tissue at different stages in carcinogenesis

  KURKOWIAK M. ARCIMOWICZ L. CHRUSCIEL E. URBAN-WOJCIUK Z. PAPAK I. KEEGAN Liam O'CONNELL Mary Anne KOWALSKI J. HUPP T. MAREK-TRZONKOWSKA N.

  Article in Periodical

  RNA Biology, year: 2021, volume: 18, edition: 11, DOI

2020

• Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila

  DENG Patricia KHAN Anzer JACOBSON Dionna SAMBRANI Nagraj MCGURK Leeanne LI Xianghua JAYASREE Aswathy HEJÁTKO Jan SHOHAT-OPHIR Galit O'CONNELL Mary Anne LI Jin Billy KEEGAN Liam

  Article in Periodical

  Nature Communications, year: 2020, volume: 11, edition: 1, DOI

• Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures

  TAN Tiong Yang SEDMÍK Jiří FITZGERALD Mark P. SUKENIK HALEVY Rivka KEEGAN Liam HELBIG Ingo BASEL-SALMON Lina COHEN Lior STRAUSSBERG Rachel CHUNG Wendy K. HELAL Mayada MAROOFIAN Reza HOULDEN Henry JUUSOLA Jane SADEDIN Simon PAIS Lynn HOWELL Katherine B. WHITE Susan M. CHRISTODOULOU John O'CONNELL Mary Anne

  Article in Periodical

  The American Journal of Human Genetics, year: 2020, volume: 106, edition: 4, DOI

• Elucidating the Biological Role of ADAR1 in the Innate immunity Response

  SINIGAGLIA Ketty MELICHEROVÁ Janka STEJSKAL Stanislav KEEGAN Liam O'CONNELL Mary Anne

  Conference abstract

  Year: 2020, type: Conference abstract

• Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy

  KHAN Anzer PARO Simona MCGURK Leeanne SAMBRANI Nagraj HOGG Marion C. BRINDLE James Paul PENNETTA Giuseppa KEEGAN Liam O'CONNELL Mary Anne

  Article in Periodical

  BMC Biology, year: 2020, volume: 18, edition: 1, DOI

• The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs

  PISKÁČEK Martin HAVELKA Marek JENDRUCHOVÁ Kristína KNIGHT Andrea KEEGAN Liam

  Article in Periodical

  Cellular and molecular life sciences, year: 2020, volume: 77, edition: 9, DOI

2019

• Activation of innate immunity by mitochondrial dsRNA in mouse cells lacking p53 protein

  WIATREK-MOUMOULIDIS Dagmara Marta CANDELA Maria Elena SEDMÍK Jiří OPPELT Jan KEEGAN Liam O'CONNELL Mary Anne

  Article in Periodical

  RNA, year: 2019, volume: 25, edition: 6, DOI

• ADAR RNA editing in innate immune response phasing, in circadian clocks and in sleep

  SINIGAGLIA Ketty WIATREK Dagmara KHAN Anzer MICHALÍK David SAMBRANI Nagraj SEDMÍK Jiří VUKIĆ Dragana O'CONNELL Mary Anne KEEGAN Liam

  Article in Periodical

  Biochimica et biophysica acta - Gene regulatory mechanisms, year: 2019, volume: 1862, edition: 3, DOI

2017

• A to I editing in disease is not fake news

  BAJAD P. JANTSCH MF KEEGAN Liam O'CONNELL Mary Anne

  Article in Periodical

  RNA BIOLOGY, year: 2017, volume: 14, edition: 9, DOI

• ADAR RNA editing below the backbone

  KEEGAN Liam KHAN Anzer VUKIĆ Dragana O'CONNELL Mary

  Article in Periodical

  RNA, year: 2017, volume: 23, edition: 9, DOI