Liam Keegan, PhD.
Senior researcher, ERA Chair - Mary O'Connell Research Group
Office: bldg. E35/143
Kamenice 753/5
625 00 Brno
Phone: | +420 549 49 5460 |
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E‑mail: |
social and academic networks: |
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Total number of publications: 19
2023
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Adenosine Deaminase Acting on RNA (ADAR) Enzymes: A Journey from Weird to Wondrous
Accounts of chemical research, year: 2023, volume: 56, edition: 22, DOI
2022
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ADAR2 enzymes: efficient site-specific RNA editors with gene therapy aspirations
RNA, year: 2022, volume: 28, edition: 10, DOI
2021
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ADAR RNA Modifications, the Epitranscriptome and Innate Immunity
Trends in Biochemical Sciences, year: 2021, volume: 46, edition: 9, DOI
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Biallelic variants in ADARB1, encoding a dsRNA-specific adenosine deaminase, cause a severe developmental and epileptic encephalopathy
Journal of Medical Genetics, year: 2021, volume: 58, edition: 7, DOI
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Interplays of different types of epitranscriptomic mRNA modifications
RNA Biology, year: 2021, volume: 18, edition: S1, DOI
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The effects of RNA editing in cancer tissue at different stages in carcinogenesis
RNA Biology, year: 2021, volume: 18, edition: 11, DOI
2020
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Adar RNA editing-dependent and -independent effects are required for brain and innate immune functions in Drosophila
Nature Communications, year: 2020, volume: 11, edition: 1, DOI
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Bi-allelic ADARB1 Variants Associated with Microcephaly, Intellectual Disability, and Seizures
The American Journal of Human Genetics, year: 2020, volume: 106, edition: 4, DOI
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Elucidating the Biological Role of ADAR1 in the Innate immunity Response
Year: 2020, type: Conference abstract
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Membrane and synaptic defects leading to neurodegeneration in Adar mutant Drosophila are rescued by increased autophagy
BMC Biology, year: 2020, volume: 18, edition: 1, DOI