prof. RNDr. Zbyněk Prokop, Ph.D.

2025

• Assessing the impact of His-tags on activity and stability of staphylokinase variants

  STULAJTEROVA Monika AMBRO Lubos SEDLAKOVA Dagmar NEMERGUT Michal KOHOUT Pavel MAZURENKO Stanislav VARHAC Rastislav STRUNGA Alan TOUL Martin PROKOP Zbyněk DAMBORSKÝ Jiří TOMKOVA Maria SEDLÁK Erik

  Article in Periodical

  International Journal of Biological Macromolecules, year: 2025, volume: 328, edition: November 2025, DOI

• Automated Engineering Protein Dynamics via Loop Grafting: Improving Renilla Luciferase Catalysis

  PLANAS IGLESIAS Joan MAJEROVÁ Marika PLUSKAL Daniel VAŠINA Michal DAMBORSKÝ Jiří PROKOP Zbyněk MAREK Martin BEDNÁŘ David

  Article in Periodical

  ACS Catalysis, year: 2025, volume: 15, edition: 4, DOI

• Biochemical and Computational Characterization of Haloalkane Dehalogenase Variants Designed by Generative AI: Accelerating the SN2 Step

  GELFAND Natalia OREL Vojtěch CUI Wenqiang DAMBORSKÝ Jiří LI Chenglong PROKOP Zbyněk XIE Wen Jun WARSHEL Arieh

  Article in Periodical

  Journal of the American Chemical Society, year: 2025, volume: 147, edition: 3, DOI

• Decoding Protein Stabilization: Impact on Aggregation, Solubility, and Unfolding Mechanisms

  HAVLÁSEK Martin MARQUES Sérgio Manuel SZOTKOWSKÁ Veronika KUNKA Antonín BABKOVÁ Petra DAMBORSKÝ Jiří PROKOP Zbyněk BEDNÁŘ David

  Article in Periodical

  Journal of Chemical Information and Modeling, year: 2025, volume: 65, edition: 16, DOI

• Engineering Dehalogenase Enzymes Using Variational Autoencoder-Generated Latent Spaces and Microfluidics

  KOHOUT Pavel VAŠINA Michal MAJEROVÁ Marika NOVÁKOVÁ Veronika DAMBORSKÝ Jiří BEDNÁŘ David MAREK Martin PROKOP Zbyněk MAZURENKO Stanislav

  Article in Periodical

  JACS AU, year: 2025, volume: 5, edition: 2, DOI

• Functional Characterization of Luciferase in a Brittle Star Indicates Parallel Evolution Influenced by Genomic Availability of Haloalkane Dehalogenase

  LAU Emily S. MAJEROVÁ Marika HENSLEY Nicholai M. MUKHERJEE Arnab VAŠINA Michal PLUSKAL Daniel DAMBORSKÝ Jiří PROKOP Zbyněk DELROISSE Jerome BAYAERT Wendy-Shirley PAREY Elise OLIVERI Paola MARLETAZ Ferdinand MAREK Martin OAKLEY Todd H.

  Article in Periodical

  Molecular Biology and Evolution, year: 2025, volume: 42, edition: 5, DOI

• Modulation of Amyloid-β Aggregation by Surface Proteins from Pathogens Associated with Alzheimer's Disease

  KUNKA Antonín HŘÍBKOVÁ Hana VÁŇOVÁ Tereza POSPÍŠILOVÁ Veronika HAVLÁSEK Martin HAVIERNIK Jan RŮŽEK Daniel DAMBORSKÝ Jiří BOHAČIAKOVÁ Dáša PROKOP Zbyněk

  Article in Periodical

  ACS Chemical Neuroscience, year: 2025, volume: 16, edition: 18, DOI

• Thrombolytic proteins profiling: High-throughput activity, selectivity, and resistance assays

  TOUL Martin STRUNGA Alan DAMBORSKÝ Jiří PROKOP Zbyněk

  Article in Periodical

  FEBS Open Bio, year: 2025, DOI

2024

• A closed 3D printed microfluidic device for automated growth and differentiation of cerebral organoids from single-cell suspension

  KANDRA Mário VÁŇOVÁ Tereza JONGEN Vincent Alexander POSPÍŠIL Jakub NOVAK Josef CHOCHOLA Václav BURYSKA Tomas PROKOP Zbyněk HODNY Zdenek HAMPL Aleš BOHAČIAKOVÁ Dáša JAROŠ Josef

  Article in Periodical

  Biotechnology Journal, year: 2024, volume: 19, edition: 8, DOI

• Azobenzene-Based Photoswitchable Substrates for Advanced Mechanistic Studies of Model Haloalkane Dehalogenase Enzyme Family

  SLÁNSKÁ Michaela ŠTACKOVÁ Lenka MARQUES Sérgio Manuel ŠTACKO Peter MARTÍNEK Marek JÍLEK Luboš TOUL Martin DAMBORSKÝ Jiří BEDNÁŘ David KLÁN Petr PROKOP Zbyněk

  Article in Periodical

  ACS Catalysis, year: 2024, volume: 14, edition: 15, DOI