Ing. Olga Švecová, Ph.D.

2026

• Field potential duration and its variability as essential parameters for revealing proarrhythmia: problematic aspects of analysis in cardiomyocytes derived from human pluripotent stem cells

  KRÁL Martin ŠVECOVÁ Olga JURAK Pavel HALAMEK Josef ŠIMURDOVÁ Milena ŠIMURDA Jiří BÉBAROVÁ Markéta

  Article in Periodical

  PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY, year: 2026, volume: 199, edition: March 2026, DOI

• Identification and functional assessment of a KCNH2 compound heterozygosity in a patient with presumed idiopathic ventricular fibrillation ascertains the diagnosis of long QT syndrome type 2

  JANKOVÁ Natálie KRÁL Martin ŠVECOVÁ Olga ZÍDKOVÁ Jana LIETAVA Samuel SLADEČEK Stanislava PACHERNÍK Jiří PÁSEK Michal NOVOTNÝ Tomáš BÉBAROVÁ Markéta

  Article in Periodical

  EP Europace, year: 2026, volume: 28, edition: 2, DOI

2025

• A variant in the SCN5A gene, M135V-Nav1.5, associated with idiopathic ventricular fibrillation: clinical, genetic, and functional data

  BÉBAROVÁ Markéta KRÁL Martin MALOVÁ Anna VAŇÁSKOVÁ Vendula ŠVECOVÁ Olga LIETAVA Samuel ZÍDKOVÁ Jana BÁRTA Tomáš SLADEČEK Stanislava PACHERNÍK Jiří NOVOTNÝ Tomáš

  Conference abstract

  Year: 2025, type: Conference abstract

• Aminophylline at clinically relevant concentrations affects inward rectifier potassium current in healthy porcine and failing human cardiomyocytes in a similar manner

  BÉBAROVÁ Markéta ŠVECOVÁ Olga KULA Roman PÁSEK Michal JEKLOVA Edita FILA Petr PEŠL Martin

  Conference abstract

  Year: 2025, type: Conference abstract

• Arytmogenní dopad varianty Y4734C v genu RYR2 asociované s idiopatickou fibrilací komor: analýza využívající pacient-specifické kardiomyocyty

  KRÁL Martin ZELENÁK Štefan ŠVECOVÁ Olga PACHERNÍK Jiří BÁRTA Tomáš ZÍDKOVÁ Jana LIETAVA Samuel NOVOTNÝ Tomáš BÉBAROVÁ Markéta

  Conference abstract

  Year: 2025, type: Conference abstract

• Association between cerebral organoid electrophysiological alterations and amyloid-β 42/40 ratio

  LIŠČÁKOVÁ Barbora ANGELOVSKI Andrijana ŠVECOVÁ Olga HŘÍBKOVÁ Hana SEDMÍK Jiří BOHAČIAKOVÁ Dáša KLIMEŠ Petr KOLAJOVÁ Martina BRÁZDIL Milan BÉBAROVÁ Markéta

  Conference abstract

  Year: 2025, type: Conference abstract

• Effect of sex hormones on patient-specific cardiomyocytes of a female patient with catecholaminergic polymorphic ventricular tachycardia

  KRÁL Martin ŠVECOVÁ Olga ZELENÁK Štefan PACHERNÍK Jiří BÁRTA Tomáš ZÍDKOVÁ Jana LIETAVA Samuel NOVOTNÝ Tomáš BÉBAROVÁ Markéta

  Conference abstract

  Year: 2025, type: Conference abstract

• Effect of specific antagomirs targeting miRNA-142-5p and miRNA-142-3p on neuroelectrophysiological parameters

  POLEDŇÁKOVÁ Anna GOLIÁŠOVÁ Zita ŠVECOVÁ Olga SHAKERZADEH Jalleh KRÁL Martin KOLAJOVÁ Martina KLIMEŠ Petr BRÁZDIL Milan BÉBAROVÁ Markéta

  Conference abstract

  Year: 2025, type: Conference abstract

• Functional analysis in three probands suffering from “true” idiopathic ventricular fibrillation

  BÉBAROVÁ Markéta KRÁL Martin JANKOVÁ Natálie ŠVECOVÁ Olga ZELENÁK Štefan PACHERNÍK Jiří BÁRTA Tomáš PÁSEK Michal ZÍDKOVÁ Jana NOVOTNÝ Tomáš

  Conference abstract

  Year: 2025, type: Conference abstract

• Functional impact of hERG variants S1021Qfs*98 and A228V associated with idiopathic ventricular fibrillation

  JANKOVÁ Natálie KRÁL Martin ŠVECOVÁ Olga PACHERNÍK Jiří SLADEČEK Stanislava NOVOTNÝ Tomáš BÉBAROVÁ Markéta

  Conference abstract

  Year: 2025, type: Conference abstract