Mgr. Michal Šmída, Dr. rer. nat.

2020

• CD20 is dispensable for B-cell receptor signaling but is required for proper actin polymerization, adhesion and migration of malignant B cells

  KOZLOVÁ Veronika LEDEREROVÁ Aneta LADUNGOVÁ Adriana PESCHELOVÁ Helena JANOVSKÁ Pavlína SLUSARCZYK A. DOMAGALA J. KOPČIL Pavel VAKULOVÁ Viera OPPELT Jan BRYJA Vítězslav DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Article in Periodical

  Plos one, year: 2020, volume: 15, edition: 3, DOI

• Combination of epigenetic drug screen and CRISPR knockout screen as an unbiased approach to reveal possible CD20 therapy improvement

  KOZLOVÁ Veronika LEDEREROVÁ Aneta MANČÍKOVÁ Veronika DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Combination of epigenetic drug screen and CRISPR knockout screen revealed involvement of aurora kinases and Cullin 3 in CD20 regulation

  LEDEREROVÁ Aneta KOZLOVÁ Veronika MANČÍKOVÁ Veronika PESCHELOVÁ Helena PERSSON J. SCHMIERER B. DOUBEK Michael MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• CRISPR/CAS9 technology: a useful tool in the study of chronic lymphocytic leukemia

  PESCHELOVÁ Helena KOZLOVÁ Veronika MANČÍKOVÁ Veronika LADUNGOVÁ Adriana HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Elucidation of factors enhancing the expression of CD20 and thereby efficiency of CD20 monoclonal antibodies through epigenetic drug screening of resistant CLL cells

  KOZLOVÁ Veronika LEDEREROVÁ Aneta MANČÍKOVÁ Veronika MAYER Jiří POSPÍŠILOVÁ Šárka DOUBEK Michael ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Genome-wide CRISPR/Cas9 screening reveals novel target genes, whose inactivation is able to upregulate surface expression of immunotherapy target CD20

  PESCHELOVÁ Helena DOSTÁLOVÁ Lenka KOZLOVÁ Veronika LEDEREROVÁ Aneta HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Impact of genetics on the performance of anti-CD 19 chimeric antigen receptor T cells in chronic lymphocytic leukemia

  MANČÍKOVÁ Veronika KOZLOVÁ Veronika PESCHELOVÁ Helena MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

• Performance of anti-CD19 chimeric antigen receptor T cells in genetically defined classes of chronic lymphocytic leukemia

  MANČÍKOVÁ Veronika PESCHELOVÁ Helena KOZLOVÁ Veronika LEDEREROVÁ Aneta LADUNGOVÁ Adriana VERNER Jan LOJA Tomáš FOLBER František MAYER Jiří POSPÍŠILOVÁ Šárka ŠMÍDA Michal

  Article in Periodical

  Journal for ImmunoTherapy of Cancer, year: 2020, volume: 8, edition: 1, DOI

• The use of CRISPR/Cas9 technology in the study of chronic lymphocytic leukemia.

  PESCHELOVÁ Helena KOZLOVÁ Veronika MANČÍKOVÁ Veronika LADUNGOVÁ Adriana HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2020, type: Conference abstract

2019

• CRISPR/Cas9 gene editing and functional screening in chronic lymphocytic leukemia

  PESCHELOVÁ Helena KOZLOVÁ Veronika HEJRET Václav ŠMÍDA Michal

  Conference abstract

  Year: 2019, type: Conference abstract