Project information
Relationship between genetic variability in candidate genes involved in angiogenesis and proliferative retinopathy in Type 2 diabetes mellitu
- Project Identification
- GP303/05/P523
- Project Period
- 1/2005 - 12/2007
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Postdoctoral projects
- MU Faculty or unit
-
Faculty of Medicine
- RNDr. Michal Beránek, Ph.D., MBA
- Keywords
- diabetes mellitus, genetic polymorphism, proliferative retinopathy
Relationship between genetic variability in candidate genes involved in angiogenesis and proliferative retiopathy in Type 2 diabetes mellitus. Proliferative diabetic retinopathy represents one of the most serious microvascular complikation of diabetes and is the most frequent cause of blindness in developed countries. Proliferative diabetic retinopathy develops as a result of impairement of retinal vessels due to metabolic changes in diabetic, especially hyperglycemia.
Publications
Total number of publications: 4
2008
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Genetic variations and plasma levels of the Gelatinase A (matrix metalloproteinase-2) and Gelatinase B (matrix metalloproteinase-9) in proliferative diabetic retinopathy
Molecular Vision, year: 2008, volume: 14, edition: 1
2007
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Genetic risk factors for diabetic nephropathy on chromosomes 6p and 7q identified by the set-association approach
Diabetologia, year: 2007, volume: 50, edition: 5
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Genetic variation and plasma level of the basic fibroblast growth factor in proliferative diabetic retinopathy
Diabetes Res Clin Pract, year: 2007, volume: 79, edition: 2
2005
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Identifikace genetických rizikových faktor diabetické nefropatie u T2DM v genech pro EDN1, LTA, RAGE a NOS3 pomocí multilokusové analýzy
Diabetologie, metabolismus, endokrinologie, výživa, year: 2005, volume: 8, edition: suppl 1