Project information

Molecular mechanisms of the cell proliferation and differentiation

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Project Identification
GD204/08/H054
Project Period
1/2008 - 12/2011
Investor / Pogramme / Project type
Czech Science Foundation
MU Faculty or unit
Faculty of Science
Other MU Faculty/Unit
Faculty of Informatics
Keywords
regulation of cell proliferation and differentiation, genomics and proteomics, plant, animal and microbial models, bioinformatics

Plants and animals evolved significantly different strategies of regulation of the cell proliferation and differentiation. Identification and comparison of molecular mechanisms driving those different strategies in plants, animals and microorganisms might contribute to the identification of their common principles. The project is based on collaboration of laboratories involved in the study of the processes of the cell proliferation and differentiation in those different model organisms including human beings. Collaboration of the laboratories with expertise in (i) molecular plant physiology, (ii) molecular mechanisms maintaining the genome stability, (iii) proliferation, differentiation and programmed cell death of cancer cells and (iv) bioinformatics will result into a multidisciplinary, while still functional team that will guarantee successful solution of scheduled tasks. Participation of multiple, recently collaborating laboratories including Core lab will allow effective employment of high-throughput instrumentation in the planned genomics and proteomics approaches.

Publications

Total number of publications: 86


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