Project information
New molecular biology and biochemical methods to monitor estrogens and other endocrine disruptors in the environment of the C.R.
(ENVISCREEN)
- Project Identification
- 2B08036
- Project Period
- 3/2008 - 12/2011
- Investor / Pogramme / Project type
-
Ministry of Education, Youth and Sports of the CR
- Health and quality of life
- MU Faculty or unit
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Faculty of Science
- prof. RNDr. Luděk Bláha, Ph.D.
- Mgr. Martin Beníšek, Ph.D.
- doc. Mgr. Klára Hilscherová, Ph.D.
- RNDr. Iva Sovadinová, Ph.D.
- Keywords
- Endocrine disruption, estrogens, reporter assays, in vitro, immunochemical methods
- Cooperating Organization
-
Veterinary Research Institurte
- Responsible person RNDr. Milan Fránek, DrSc.
The project will lead to development of new progressive methods for screening and evaluation of endocrine disruptors in the environment that will be designed and optimized in concordance with current and newly prepared OECD standards.
Publications
Total number of publications: 29
2018
2014
2013
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Estrogen-, androgen- and aryl hydrocarbon receptor mediated activities in passive and composite samples from municipal waste and surface waters
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In vitro effects of pollutants from particulate and volatile fractions of air samples-day and night variability
2012
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Enantioselective effects of alpha-hexachlorocyclohexane (HCH) isomers on androgen receptor activity in vitro.
Chemosphere, year: 2012, volume: 86, edition: 1, DOI
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Estrogenic activity in extracts and exudates of cyanobacteria and green algae.
Environment International, year: 2012, volume: 39, edition: 1, DOI
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Changes in concentrations of hydrophilic organic contaminants and of endocrine-disrupting potential downstream of small communities located adjacent to headwaters.
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POCIS sampling in combination with ELISA: Screening of sulfonamide residues in surface and waste waters
Journal of Environmental Monitoring, year: 2012, volume: 14, edition: 1, DOI
2011
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In vitro modulation of intracellular receptor signaling and cytotoxicity induced by extracts of cyanobacteria, complex water blooms and their fractions.
Aquatic toxicology, year: 2011, volume: 105, edition: 3-4, DOI
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The effects of PAHs and N-PAHs on retinoid signalling and Oct-4 expression in vitro.
Toxicology Letters, year: 2011, volume: 200, edition: 3, DOI