Nove přístupy pro studium afinitních interakcí založené na kapilární elektroforéze
- Project Identification
- GA19-08358S
- Project Period
- 1/2019 - 12/2021
- Investor / Pogramme / Project type
-
Czech Science Foundation
- Standard Projects
- MU Faculty or unit
- Faculty of Science
Hlavním cílem tohoto projektu je vývoj nových přístupů založených na kapilární elektroforéze pro studium afinitních interakcí plazmatických bílkovin s léčivy charakterizovanými vysokou průchodností, plnou automatizací a nízkou spotřebou vzorku.
Publications
Total number of publications: 12
2021
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Toward an automated workflow for the study of plasma protein-drug interactions based on capillary electrophoresis-frontal analysis combined with in-capillary mixing of interacting partners
Journal of Chromatography A, year: 2021, volume: 1635, edition: January 2021, DOI
2020
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Aldehyde Oxidase Assay by CE: from off-line, on-line up to immobilized enzyme reactor
Journal of Separation Science, year: 2020, volume: 43, edition: 17, DOI
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Analytical approaches for the determination of deferiprone and its iron (III) complex: Investigation of binding affinity based on liquid chromatography-mass spectrometry (LC-ESI/MS) and capillary electrophoresis-frontal analysis (CE/FA)
Microchemical Journal, year: 2020, volume: 154, edition: May 2020, DOI
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Applicability of capillary electrophoresis-frontal analysis for displacement studies: effect of several drugs on L-tryptophan and lidocaine binding to human serum albumin
Journa of Separation Science, year: 2020, volume: 43, edition: 22, DOI
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Capillary electrophoresis-based immunoassay and aptamer assay: A review
Electrophoresis, year: 2020, volume: 41, edition: 7-8, DOI
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Homocyclic o-dicarboxaldehydes: derivatization reagents for sensitive analysis of amino acids and related compounds by capillary and microchip electrophoresis
Electrophoresis, year: 2020, volume: 41, edition: 21-22, DOI
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USING OF CEFA-MS METHOD FOR BINDING CONSTANT EVALUATION
Year: 2020, type: Conference abstract
2019
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Amino acid analysis by capillary electrophoresis with fluorescence detection: Applications in finding biomarkers of schizophrenia and in human embryo viability assessment
Year: 2019, type: Conference abstract
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Automated workflow for the study of drug-protein interactions based on capillary electrophoresis-frontal analysis combined with in-capillary mixing of interacting partners
Year: 2019, type: Conference abstract
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Capillary electrophoresis-based approaches for the study of affinity interactions combined with various sensitive and non-traditional detection techniques
Electrophoresis, year: 2019, volume: 40, edition: 5, DOI