Project information

Exploring clonal evolution and causes of modern targeted therapy failure in CLL

Project Identification
MUNI/IGA/1640/2020
Project Period
1/2021 - 12/2021
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Medicine

The aim of the project is to study a mutation profile in patients with chronic lymphocytic leukemia (CLL) - a diagnosis with highly heterogenous genetic background and overal survival of patients. We plan to explore somatic mutations expanding after a specific type of therapy and correlate such mutations with consequent disease evolution. This could help with tailoring further therapy lines in order to eliminate the risk of development of therapy resistance.

Publications

Total number of publications: 7


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