Project information
Derivatization strategies revealing metabolic patterns in human pluripotent stem cells and progenitors by mass spectrometry (Stem cells metabolites derivatization)

Project Identification
Project Period
1/2022 - 12/2022
Investor / Pogramme / Project type
Masaryk University
MU Faculty or unit
Faculty of Science

Metabolites are intermediate or terminal products of cell biochemical pathways. Changes in metabolites reflect the state of cell physiology, including proliferation or differentiation. The proposed project will use one-step chemical derivatization for mass spectrometry detection of different metabolites to reveal metabolic states of pluripotent stem cells and derivatives in standard 2D (in solution derivatization) and advanced 3D cultures of stem cells and derivatives (on tissue derivatization).


Total number of publications: 2

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